Former Toronto Blue Jays in the 2021 Playoffs

Atlanta's Baseball Club

• Jesse Chavez

• Travis d'Arnaud (minor leagues)

• Sal Fasano

• Tomás Pérez

• Kevin Seitzer

• Alex Anthopoulos (GM)

Houston Cheaters

• Aledmys Díaz

• Kendall Graveman

Boston Red Sox

Eliminated by the Houston Cheaters in the ALCS on October 22nd, 2021.

• Tanner Houck (drafted)

• Travis Shaw

• Bob Brenly

• Dave Bush

• Tim Hyers (drafted)

• Ramón Vázquez (as a minor leaguer)

New York Yankees

Eliminated by the Boston Red Sox in the AL Wild Card Game on October 5th, 2021.

• Chad Green (drafted)

• Gio Urshela

• Tim Locastro (drafted)

St. Louis Cardinals

Elimiated by the Los Angeles Dodgers in the NL Wild Card Game on October 6th, 2021.

• J.A. Happ (inactive roster)

• Wade LeBlanc (as a minor leaguer)

• Justin Miller (as a minor leaguer, did not play a game)

• Stubby Clapp (hired as the hitting coach for the Dunedin Blue Jays)

Los Angeles Dodgers

Eliminated by Atlanta's Baseball Club in the NLCS on October 23rd, 2021

• Billy McKinney

• David Price (inactive roster)

• Clayton McCullough (manager in the Blue Jays minor league organization)

Chicago White Sox

Eliminated by the Houston Cheaters in the ALDS on October 12th, 2021.

• Ryan Tepera

• Miguel Cairo

• Liam Hendriks

• Howie Clark

• Shelley Duncan

• Frank Menechino

• Jimmy Cordero

Tampa Bay Rays

Eliminated by the Boston Red Sox in the ALDS on October 11th, 2021.

• Kevin Cash

• Chad Mottola

Milwaukee Brewers

Eliminated by Atlanta's Baseball Club in the NLDS on October 12th, 2021.

• Luke Maile

• Rowdy Tellez

• Daniel Vogelbach

• Daniel Norris

• Quintin Berry (minor leagues)

• Steve Karsay (drafted)

• Jason Lane (minor leageues)

• John Axford

• Ángel Perdomo (minor leagues)

San Francisco Giants

Eliminated by the Los Angeles Dodgers in the NLDS on October 14th, 2021.

• Anthony DeSclafani (drafted)

• Dominic Leone

• Kris Bryant (drafted)

• Tyler Chatwood

• Tyler Beede (drafted)