Feature requests:

• programmable muting
• mute a list of people for the duration of a live TV event, like the people who talk about baseball, starting at pre-determined times
• MLB schedules are available in advance, so you could mute Blue Jays fans from game start until about 3 hours later
• sentiment detection: mute this person while they're in a certain mood
• mute all people with a certain mood
• IBM tutorial on building sentiment analysis using tweets as the content: http://www.ibm.com/developerworks/library/wa-nodejs-app/index.html
• take whatever happens to be trending, and mute that
• https://dev.twitter.com/rest/reference/get/trends/place with the parameter of 1 gets worldwide trends
• topic muting: figure out what a person is talking about (baseball, for example) based on keywords from the tweet, and mute their tweets about that topic
• is there an API for content analysis when the content is that short?
• https://twitter.com/fakepop/status/345615079473037312
• Tweetbot-style app muting (they just look at the app name in the tweet object)
• image detection
• image matching (say, the Darth Vader selfie)
• image detection (image contains Darth Vader)
• shorter durations than 1 day
• sometimes someone is on a tweetstorm, and muting for an hour will be just fine
• Tweetbot uses an expiry time internally for non-forever muting, and displays a duration
• keywords or hashtags by an individual person
• from:sillygwailo drupal
• all tweets that contain a hashtag (any hashtag) but only by a person
• from:sillygwailo -#
• mute a specific tweet that is getting RTed a lot.
• apply mute filters to quoted tweets.
• Quiet Time is a great start, and it's open source, and uses Twitter's native muting.